RTP Research Fellow - Psychology
Location: Rochester
Posted on: June 23, 2025
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Job Description:
Mayo Clinic is top-ranked in more specialties than any other
care provider according to U.S. News & World Report. As we work
together to put the needs of the patient first, we are also
dedicated to our employees, investing in competitive compensation
and comprehensive benefit plans – to take care of you and your
family, now and in the future. And with continuing education and
advancement opportunities at every turn, you can build a long,
successful career with Mayo Clinic. You’ll thrive in an environment
that supports innovation, is committed to ending racism and
supporting diversity, equity and inclusion, and provides the
resources you need to succeed. Benefits Highlights • Medical:
Multiple plan options. • Dental: Delta Dental or reimbursement
account for flexible coverage. • Vision: Affordable plan with
national network. • Pre-Tax Savings: HSA and FSAs for eligible
expenses. • Retirement: Competitive retirement package to secure
your future. Responsibilities Dr. Ming-Fen Ho’s lab is looking for
highly motivated and productive postdoctoral fellows for stem cell
research projects within the Department of Psychiatry and
Psychology at Mayo Clinic, Rochester, MN. This study is designed to
identify novel therapeutics for substance use disorders. We will
apply novel network biology approaches, pathway modeling, and
simulation computational tools to prioritize potential candidates
for functional genomic studies. The approaches we are taking could
help us to develop mechanistic hypothesis for experimental
validation. Our findings will enhance the general understanding of
drug mechanism(s) of action and the underlying the pathophysiology
responsible for substance use disorders, thus opening new avenues
for discovering novel therapeutic targets for the treatment of
substance use disorders. Dr. Ho’s laboratory has established
protocols for differentiating human iPSCs into a variety of cell
types, including neurons, astrocytes, and brain organoids, and has
developed cellular models and cell therapeutic candidates for
diseases including alcohol use disorder, and opioid use disorder.
Qualifications • Basic education, experience and skills required
for consideration: • The successful applicant should have completed
a PhD or MD in biology, neuroscience, pharmacology, or a related
field. While ideal candidates should have expertise in one of the
following areas, we also appreciate candidates in other fields who
are committed to learning new skills and keen to bring their unique
expertise to study neuropsychiatric disorders in a collaborative
environment. • The ability to work independently, to participate in
highly collaborative projects, and to contribute intellectually to
the development of the research and process development are
requisites for this position. • Experience in basic fundamental
molecular biology techniques (such as gel electrophoresis, Western
blotting, qPCR, molecular cloning, CRISPR editing, plasmid
construction, virus packing, iPSC culture, RNA-sequencing,
multi-omics studies). • Candidates are expected to lead a project
and establish collaborative research and must have excellent verbal
and written communication skills. Key Responsibilities include: •
The postdoctoral fellow will lead a project on human iPSC-based
disease modeling and therapeutic development for neuropsychiatric
disorders such as alcohol use disorder and opioid use disorder. •
The postdoctoral fellow is expected to write progress reports and
high-quality manuscripts for publication. Applying for postdoctoral
fellowship and participating in grant applications are encouraged.
Dr. Ho will provide training for iPSC generation and maintenance,
and lab techniques for functional genomic studies. The postdoctoral
fellow will be responsible for routine cell culture for iPSCs and
brain organoids i.e. these cells require renew culture media daily.
The postdoctoral fellow will use the data generated from the
scRNA-seq and generate hypothesis and test in the lab. She/he will
work closely with Dr. Ho for this grant to pursue the function and
mechanisms of genes and pathways identified in the course of this
project. She/he will have their own projects and build their
bibliography during their postdoctoral training.
Keywords: , Coon Rapids , RTP Research Fellow - Psychology, Healthcare , Rochester, Minnesota
